Protected Nucleosides
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine
Quick view. A uridine derivative bearing 5'-O-(4,4'-dimethoxytrityl) and 3'-O-tert-butyldimethylsilyl protecting groups, identified by CAS 81246-81-3. CAS 81246-81-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine is classified as protected nucleosides (Formula C36H44N2O8Si; molecular weight 660.80).
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine is associated with uridine-containing substrates for U-position incorporation in RNA or modified RNA studies.
For 5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMTr-3'-O-TBDMS-uridine
Useful catalog search terms
- CAS 81246-81-3
- PubChem CID 14375994
Physicochemical data
| PubChem CID | 14375994 |
|---|---|
| InChIKey | ZATGYRPVDYINRF-WXQJYUTRSA-N |
| Nucleoside scaffold | uridine |
| Sugar protection | 5'-O-DMTr; 3'-O-TBDMS |
| Hydroxyl state | free 2' hydroxyl |
| InChI | InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-29(45-33(31(32)40)38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13-17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0289 and CAS 81246-81-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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