Halogenated Nucleosides
5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine
Quick view. A 5'-O-DMTr-protected 5-iodouridine building block for structure-specific protected nucleoside and nucleotide synthesis research. CAS 158728-68-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine is classified as halogenated nucleosides (Formula C30H29IN2O8; molecular weight 672.46).
5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine — 5'-O-DMTr-protected 5-iodouridine building block for structure-specific protected nucleoside and nucleotide synthesis research.
For 5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-5-I-U
- 5'-DMT-5-I-U
- 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-iodouridine
Useful catalog search terms
- CAS 158728-68-8
Physicochemical data
| Systematic designation | 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione |
|---|---|
| Nucleobase modification | 5-iodo |
| Protecting group | 5'-O-(4,4'-dimethoxytrityl) |
| InChIKey | GOLQPGCNIAQGQO-IYUNARRTSA-N |
| InChI | InChI=1S/C30H29IN2O8/c1-38-21-12-8-19(9-13-21)30(18-6-4-3-5-7-18,20-10-14-22(39-2)15-11-20)40-17-24-25(34)26(35)28(41-24)33-16-23(31)27(36)32-29(33)37/h3-16,24-26,28,34-35H,17H2,1-2H3,(H,32,36,37)/t24-,25-,26-,28-/m1/s1 |
| SMILES | COC1=CC=C(C=C1)C(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(C(=C1)I)=O)=O)O)O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC |
| Canonical SMILES | COC1=CC=C(C=C1)C(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(C(=C1)I)=O)=O)O)O)(C1=CC=CC=C1)C1=CC=C(C=C1)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for 5'-O-(4,4'-Dimethoxytrityl)-5-iodouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0043 and CAS 158728-68-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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