Other Phosphoramidites
5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz) Bis(phosphoramidite)
Quick view. A protected 2'-O-MOE-5-methylcytidine building block containing two linked phosphoramidite phosphorus centers. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz) Bis(phosphoramidite) is classified as protected modified-nucleoside bis(phosphoramidite) (Formula C58H78N6O12P2; molecular weight 1113.24).
5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz) Bis(phosphoramidite) is relevant to high-stability antisense oligonucleotide gapmer and affinity-tuning research.
For 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz) Bis(phosphoramidite), mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-2'-O-MOE-5-Me-rC(Bz) bis(phosphoramidite)
Useful catalog search terms
- C58H78N6O12P2
Physicochemical data
| Nucleoside modification | 2'-O-MOE-5-methylcytidine |
|---|---|
| Protecting groups | 5'-O-DMTr; N4-benzoyl |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz) Bis(phosphoramidite) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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BX-OP-0007Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite
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BX-OP-0008Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite
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Frequently asked questions
Can the package size for 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz) Bis(phosphoramidite) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0002, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Other Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.