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Protected Nucleosides

5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine

Quick view. A protected guanosine intermediate bearing 5'-O-DMT, 2'-O-TBDMS and N2-dimethylformamidine groups, CAS 126922-61-0. CAS 126922-61-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of 5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine
Chemical structure
Catalog numberBX-PN-0143
CAS number126922-61-0
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine is classified as protected nucleosides (Formula C40H50N6O7Si; molecular weight 754.96).

Typical application

5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine — A supplier aggregate describes this protected guanosine as an intermediate for RNA oligonucleotide synthesis.

Handling focus

For 5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

Registry nameGuanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-
Protecting groups5'-O-DMT; 2'-O-TBDMS; N2-dimethylformamidine
3' positionFree hydroxyl; not a phosphoramidite
PubChem CID136380617
InChIKeyQLIITSYHYKRUSO-SPBWOXKUSA-N
InChIInChI=1S/C40H50N6O7Si/c1-39(2,3)54(8,9)53-34-33(47)31(52-37(34)46-25-41-32-35(46)43-38(44-36(32)48)42-24-45(4)5)23-51-40(26-13-11-10-12-14-26,27-15-19-29(49-6)20-16-27)28-17-21-30(50-7)22-18-28/h10-22,24-25,31,33-34,37,47H,23H2,1-9H3,(H,43,44,48)/t31-,33-,34-,37-/m1/s1
SMILESCC(C)(C)[Si](C)(C)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N=CN(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for 5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-PN-0143 and CAS 126922-61-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

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