Halogenated Nucleosides
5'-O-DMTr-5-Iodo-2'-deoxyuridine
Quick view. We supply 5'-O-DMTr-5-Iodo-2'-deoxyuridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 104375-88-4. Catalog target purity: Specification on request.
Product profile
5'-O-DMTr-5-Iodo-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C30H29IN2O7; molecular weight 656.46).
5'-O-DMTr-5-Iodo-2'-deoxyuridine — 2’-Deoxy-5’-O-DMT-5-iodouridine is a modified oligonucleotides designed for use in genetic analysis and RNA detection.
For 5'-O-DMTr-5-Iodo-2'-deoxyuridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- SCHEMBL3599668
- DMT-5-I-dU
- DMT-5-I-2'-deoxyuridine
- 5'-DMT-5-I-2'-deoxyuridine
- 5'-DMT-5-iodo-deoxyuridine
- 2'-Deoxy-5'-O-DMT-5-iodouridine
- 5'-O-DMT-5-iodo-2'-deoxyuridine
- 5-Iodo-5'-diMethoxytrityl-2'-deoxyuridine
Useful catalog search terms
- CAS 104375-88-4
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- Halogenated Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|---|
| InChI | InChI=1S/C30H29IN2O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-26-25(34)16-27(40-26)33-17-24(31)28(35)32-29(33)36/h3-15,17,25-27,34H,16,18H2,1-2H3,(H,32,35,36)/t25-,26+,27+/m0/s |
| InChIKey | RLDUYGSOCGOJTP-SKDNVIITNA-N |
| SMILES | C(OC[C@@H]1[C@@H](O)C[C@H](N2C=C(C(=O)NC2=O)I)O1)(C1C=CC=CC=1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,4,7,r| |
| Melting point | >128 °C (decomp) |
| Density | 1.60±0.1 g/cm3(Predicted) |
| pKa | 7.94±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5'-O-DMTr-5-Iodo-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-DMTr-5-Iodo-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0007 and CAS 104375-88-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.