Protected Nucleosides
5'-O-Tritylthymidine
Quick view. We supply 5'-O-tritylthymidine as a protected nucleoside intermediate for selective nucleoside and oligonucleotide building-block synthesis. CAS 7791-71-1. Catalog target purity: ≥97%.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5'-O-Tritylthymidine is classified as nucleoside or protected nucleoside intermediate (Formula C29H28N2O5; molecular weight 484.54).
5'-O-Tritylthymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-Tritylthymidine, storage: Store sealed and dry at approximately 5 °C unless the current lot CoA specifies otherwise. Form: Solid.
Names and search terms
Confirmed or normalized name variants
- 5'-O-Trityl-2'-deoxythymidine
- 5'-Tritylthymidine
- 5'-O-Tr-dT
- Trt-dT
- 5'-O-Trt-deoxythymidine
- 5'-Trt-2'-deoxythymidine
- 5''-O-TRITYLTHYMIDINE(5-OTT)
- 5'-O-Triphenylmethylthymidine
Useful catalog search terms
- CAS 7791-71-1
- Nucleoside or protected nucleoside intermediate
- Protected Nucleosides
Physicochemical data
| Purity basis | Research-grade target; the lot-specific CoA reports the release result and analytical method. |
|---|---|
| Protecting group | 5'-O-trityl |
| Supply form | Dry research material |
| Melting point | 125 °C(Solv: acetone (67-64-1); ethyl ether (60-29-7)) |
| Density | 1.275±0.06 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-Tritylthymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0011 and CAS 7791-71-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.