Amino-modified Nucleosides
6-Deaminoadenosine, Nebularine
Quick view. We supply 6-Deaminoadenosine, Nebularine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 550-33-4. Catalog target purity: ≥95%.
Product profile
6-Deaminoadenosine, Nebularine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12N4O4; molecular weight 252.23).
6-Deaminoadenosine, Nebularine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 6-Deaminoadenosine, Nebularine, reported solubility: DMSO (Slightly), Ethanol, Methanol (Slightly). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- nebularine
- NSC65423
- Purinosine
- ribosyl-purin
- ribosylpurine
- PURINE RIBOSIDE
- Ribosyl-isopurine
- 6-deaMinoadenosine
Useful catalog search terms
- CAS 550-33-4
- Nucleoside or protected nucleoside intermediate
- amine functionality
- BX-AMN-0095
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| SMILES | OCC1OC(C(O)C1O)N1C=NC2=C1N=CN=C2 |
| Identity note | CAS and structure correspond to 6-deaminoadenosine (nebularine); confirm hydration and salt form on the current specification. |
| InChI | InChI=1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s |
| InChIKey | MRWXACSTFXYYMV-FDDDBJFASA-N |
| Melting point | 181-182°C |
| Boiling point | 395.4°C (rough estimate) |
| Density | 1.3402 (rough estimate) |
| pKa | 13.13±0.70(Predicted) |
| Form | Solid |
| Color | Pale Beige to Beige |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 6-Deaminoadenosine, Nebularine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 6-Deaminoadenosine, Nebularine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0103 and CAS 550-33-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.