Modified Nucleosides
6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine
Quick view. We supply 6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2239-64-7. Catalog target purity: Specification on request.
Product profile
6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12N4O3S; molecular weight 268.29).
6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine, storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione
- dI6S
- DEOXYTHIOINOSINE
- 2’-deoxy-6-thio-inosin
- 2’-deoxy-6-thioinosine
- Inosine, 2'-deoxy-6-thio-
- 6-mercaptopurinedeoxyriboside
- 6-MERCAPTOPURINE-2'-DEOXYRIBOSIDE
Useful catalog search terms
- CAS 2239-64-7
- Nucleoside or protected nucleoside intermediate
- sulfur/thiol functionality
- Modified Nucleosides
Physicochemical data
| Key chemistry motifs | sulfur/thiol functionality |
|---|---|
| InChI | InChI=1S/C10H12N4O3S/c15-2-6-5(16)1-7(17-6)14-4-13-8-9(14)11-3-12-10(8)18/h3-7,15-16H,1-2H2,(H,11,12,18)/t5-,6+,7+/m0/s |
| InChIKey | WACLJMMBCDNRJE-RRKCRQDMSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2NC=NC3=S)CO)O |
| Melting point | 184-186 °C |
| Boiling point | 665.9±65.0 °C(Predicted) |
| Density | 1.87±0.1 g/cm3(Predicted) |
| pKa | 8.40±0.20(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe 6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0382 and CAS 2239-64-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 6-Mercapto-9-(2'-deoxy-beta-D-ribofuranosyl)purine or the named structural feature represented by this product.