Modified Nucleosides
7-Cyano-7-deazaguanosine
Quick view. We supply 7-Cyano-7-deazaguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 61210-21-7. Catalog target purity: Specification on request.
Product profile
7-Cyano-7-deazaguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C12H13N5O5; molecular weight 307.27).
7-Cyano-7-deazaguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 7-Cyano-7-deazaguanosine, reported solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly). Form: Solid.
Names and search terms
Confirmed or normalized name variants
- 2-Amino-4,7-dihydro-4-oxo-7-β-D-ribofuranosyl-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
- preQ nucleoside
- 7-Cyano-7-deazaguanosine, Natural product Pre-Q0
- 7-Cyano-7-deazaguanosine Natural product Pre-Q0, RNA-modified nucleoside
Useful catalog search terms
- CAS 61210-21-7
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C12H13N5O5/c13-1-4-2-17(9-6(4)10(21)16-12(14)15-9)11-8(20)7(19)5(3-18)22-11/h,5,7-8,11,18-20H,3H2,(H3,14,15,16,21)/t5-,7-,8-,11-/m1/s |
|---|---|
| InChIKey | BIRQNXWAXWLATA-IOSLPCCCSA-N |
| SMILES | O[C@H]1[C@H](N2C3=C(C(C#N)=C2)C(=O)N=C(N)N3)O[C@H](CO)[C@H]1O |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 7-Cyano-7-deazaguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0614 and CAS 61210-21-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.