Amino-modified Nucleosides
8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine
Quick view. We supply 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 1134156-31-2. Catalog target purity: Specification on request.
Product profile
8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine is classified as nucleoside or protected nucleoside intermediate (Formula C25H23Cl2N7O4; molecular weight 556.4).
8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine, reported solubility: DMSO: >10mg/mL. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]-9-purinyl]-3,4-dihydroxy-2-oxolanyl]methoxymethyl]benzonitrile
- CS-1647
- VER 155008
- VER 155088
- HSP70 inhibitor
- 8-(3,4-Dichlorobenzyl)amino-5’-O-(4-cyanobenzyl)adenosine, VER155008
- 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
- Adenosine, 5'-O-[(4-cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-
Useful catalog search terms
- CAS 1134156-31-2
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C25H23Cl2N7O4/c26-16-6-5-15(7-17(16)27)9-30-25-33-19-22(29)31-12-32-23(19)34(25)24-21(36)20(35)18(38-24)11-37-10-14-3-1-13(8-28)2-4-14/h1-7,12,18,20-21,24,35-36H,9-11H2,(H,30,33)(H2,29,31,32)/t18-,20-,21-,24-/m1/s |
| InChIKey | ZXGGCBQORXDVTE-UMCMBGNQSA-N |
| SMILES | O(CC1=CC=C(C#N)C=C1)C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2NCC2=CC=C(Cl)C(Cl)=C2)[C@H](O)[C@@H]1O |
| Boiling point | 856.3±75.0 °C(Predicted) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| pKa | 13.04±0.70(Predicted) |
| Form | powder |
| Color | white to light brown |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0011 and CAS 1134156-31-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.