Amino-modified Nucleosides
8-Amino-2'-deoxyadenosine
Quick view. We supply 8-Amino-2'-deoxyadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 13389-09-8. Catalog target purity: Specification on request.
Product profile
8-Amino-2'-deoxyadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O3; molecular weight 266.26).
8-Amino-2'-deoxyadenosine — 8-Amino-2’-deoxyadenosine is derived from 8-Azido-2’-deoxyadenosine which is needed for the preparation of oligonucleotides. Also, it is base-paired with 2’-deoxythymidine which may have important significance for designing novel DNA duplexes and triplexes.
For 8-Amino-2'-deoxyadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 9-(2-Deoxypentofuranosyl)-8-imino-8,9-dihydro-7H-purin-6-amine
- Adenosine, 8-amino-2'-deoxy-
- 5-(6,8-DIAMINOPURIN-9-YL)-2-(HYDROXYMETHYL)OXOLAN-3-OL
Useful catalog search terms
- CAS 13389-09-8
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C10H14N6O3/c11-8-7-9(14-3-13-8)16(10(12)15-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,15)(H2,11,13,14) |
| InChIKey | KHQCCEUMCUSZKM-UHFFFAOYSA-N |
| SMILES | N=c1[nH]c2c(N)ncnc2n1C1CC(O)C(CO)O1 |
| Boiling point | 698.2±65.0 °C(Predicted) |
| Density | 2.08±0.1 g/cm3(Predicted) |
| pKa | 13.76±0.60(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 8-Amino-2'-deoxyadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 8-Amino-2'-deoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 8-Amino-2'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0017 and CAS 13389-09-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.