Amino-modified Nucleosides
8-Aminoguanosine
Quick view. A guanosine derivative bearing an amino substituent at purine C8, identified by CAS 3868-32-4. CAS 3868-32-4. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
8-Aminoguanosine is classified as amino-modified nucleosides (Formula C10H14N6O5; molecular weight 298.26).
8-Aminoguanosine — Referenced in published studies of purine nucleoside phosphorylase and purine-metabolism biology.
For 8-Aminoguanosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2,8-Diaminoinosine
- Guanosine, 8-amino-
- NSC-90390
Useful catalog search terms
- CAS 3868-32-4
- PubChem CID 135518164
Physicochemical data
| PubChem CID | 135518164 |
|---|---|
| InChIKey | FNXPTCITVCRFRK-UMMCILCDSA-N |
| UNII | SHO2CA1BRO |
| Nucleoside scaffold | guanosine |
| Modification | 8-amino |
| InChI | InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1 |
| SMILES | C([C@@H]1[C@H]([C@H]([C@@H](O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 8-Aminoguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 8-Aminoguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0117 and CAS 3868-32-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
- Purine Nucleoside Phosphorylase Inhibition Rebalances Purine Metabolism and Attenuates Organ Damage in Sickle Cell Mice
- 8-Aminoguanosine Exerts Diuretic, Natriuretic, and Glucosuric Activity via Conversion to 8-Aminoguanine, Yet Has Direct Antikaliuretic Effects
- A nucleoside-based supramolecular hydrogel integrating localized self-delivery and immunomodulation for periodontitis treatment
- Biochemical pathways of 8-aminoguanine production in Sprague-Dawley and Dahl salt-sensitive rats
- 8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.