Modified Nucleosides
8-Azaguanosine
Quick view. We supply 8-Azaguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2133-80-4. Catalog target purity: Specification on request.
Product profile
8-Azaguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C9H12N6O5; molecular weight 284.23).
8-Azaguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Azaguanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5-Imino-3-pentofuranosyl-4,5-dihydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol
- Azaguanosine
- 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-v-triazolo[4,5-d]pyrimidin-7-one
- 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one
- 5-Amino-3,4-dihydro-3-(β-D-ribofuranosyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one
- 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-3-β-D-ribofuranosyl-
Useful catalog search terms
- CAS 2133-80-4
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| SMILES | O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(N=C(N)NC3=O)=C3N=N2 |
|---|---|
| Identity note | CAS identifies the neutral 8-azaguanosine nucleoside; confirm hydration and salt form on the current specification. |
| InChI | InChI=1/C9H12N6O5/c10-9-12-5-2(6(18)13-9)11-1-15(5)8-4(17)3(16)7(14-19)20-8/h,3-4,7-8,14,16-17,19H,(H3,10,12,13,18)/t3-,4+,7-,8+/s |
| InChIKey | DGHTWAQOVOJABA-BKVVLWDVNA-N |
| Melting point | 250-252 °C (decomp)(Solv: water (7732-18-5)) |
| Density | 2.49±0.1 g/cm3(Predicted) |
| pKa | 8.32±0.20(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Azaguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0678 and CAS 2133-80-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.