Halogenated Nucleosides
8-Bromo-2'-deoxyadenosine
Quick view. We supply 8-Bromo-2'-deoxyadenosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 14985-44-5. Catalog target purity: Specification on request.
Product profile
8-Bromo-2'-deoxyadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12BrN5O3; molecular weight 330.14).
8-Bromo-2'-deoxyadenosine — 8-Bromo-2’deoxyadenosine is a brominated DNA adducts generated by human DNA polymerases.
For 8-Bromo-2'-deoxyadenosine, reported solubility: Soluble in DMSO or DMF. Storage: -20°C, protect from light.
Names and search terms
Confirmed or normalized name variants
- 8-Br-dA
- 8-Br-2'-dA
- 8-Bromodeoxyadenosine
- Adenosine,8-bromo-2'-deoxy-
- 8-BROMO-2'-DEOXY-D-ADENOSINE
- -5-(6-Amino-8-bromo-9H-purin-9-yl)
- 8-BROMO-2'-DEOXYADENOSINE USP/EP/BP
- 8-Bromo-9-(2'-deoxyribofuranosyl)adenine
Useful catalog search terms
- CAS 14985-44-5
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H12BrN5O3/c11-10-15-7-8(12)13-3-14-9(7)16(10)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,13,14) |
|---|---|
| InChIKey | NJBIVXMQFIQOGE-UHFFFAOYSA-N |
| SMILES | Nc1ncnc2c1nc(Br)n2C1CC(O)C(CO)O1 |
| Melting point | 202 °C |
| Boiling point | 671.0±65.0 °C(Predicted) |
| Density | 2.3 |
| Form | Powder |
| Color | White to Yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 8-Bromo-2'-deoxyadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Bromo-2'-deoxyadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0039 and CAS 14985-44-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.