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Modified Nucleosides

8-Hydroxymethylguanosine

Quick view. A guanosine ribonucleoside bearing a hydroxymethyl substituent at the 8-position of the purine base. CAS 54898-41-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Chemical structure of 8-Hydroxymethylguanosine
Chemical structure
Catalog numberBX-MN-0582
CAS number54898-41-8
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

8-Hydroxymethylguanosine is classified as c8-substituted guanosine nucleoside (Formula C11H15N5O6; molecular weight 313.27 g/mol).

Typical application

8-Hydroxymethylguanosine is associated with guanine-containing building blocks or substrates for G-position incorporation and analytical comparison.

Handling focus

For 8-Hydroxymethylguanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Useful catalog search terms

Physicochemical data

PubChem CID135779019
IUPAC name2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-(hydroxymethyl)-1H-purin-6-one
InChIKeyPQGSVCVISXGQOL-KAFVXXCXSA-N
InChIInChI=1S/C11H15N5O6/c12-11-14-8-5(9(21)15-11)13-4(2-18)16(8)10-7(20)6(19)3(1-17)22-10/h3,6-7,10,17-20H,1-2H2,(H3,12,14,15,21)/t3-,6-,7-,10-/m1/s1
SMILESC([C@@H]1[C@H]([C@H]([C@@H](O1)N2C(=NC3=C2N=C(NC3=O)N)CO)O)O)O

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for 8-Hydroxymethylguanosine be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-MN-0582 and CAS 54898-41-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.