Halogenated Nucleosides
9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine
Quick view. A protected, 3'-deoxy-3'-fluoro 6-chloropurine nucleoside building block for structure-specific synthesis research. CAS 1612192-06-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine is classified as halogenated nucleosides (Formula C20H18ClFN4O5; molecular weight 448.84).
9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine — Protected, fluorinated 6-chloropurine nucleoside building block for structure-specific synthesis research.
For 9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 9-(2-O-Acetyl-5-O-toluyl-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine
Useful catalog search terms
- CAS 1612192-06-9
- 2-O-acetyl 5-O-p-toluoyl 3-fluoro 6-chloropurine nucleoside
- ZGDFADBOEZXSJY-NPNMTCQASA-N
- PubChem CID 118705322
Physicochemical data
| Sugar modification | 3'-deoxy-3'-fluoro |
|---|---|
| Sugar protection | 2'-O-acetyl; 5'-O-(p-toluoyl) |
| Purine substitution | 6-chloro |
| PubChem CID | 118705322 |
| InChIKey | ZGDFADBOEZXSJY-NPNMTCQASA-N |
| InChI | InChI=1S/C20H18ClFN4O5/c1-10-3-5-12(6-4-10)20(28)29-7-13-14(22)16(30-11(2)27)19(31-13)26-9-25-15-17(21)23-8-24-18(15)26/h3-6,8-9,13-14,16,19H,7H2,1-2H3/t13-,14-,16-,19-/m1/s1 |
| SMILES | CC1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=CN=C4Cl)OC(=O)C)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 9-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-chloro-9H-purine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0057 and CAS 1612192-06-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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