Halogenated Nucleosides
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-(thiophen-3-yl)purine
Quick view. A 3'-deoxy-3'-fluoro, 6-(thiophen-3-yl) purine nucleoside building block for structure-specific nucleoside and oligonucleotide synthesis research. CAS 1612191-90-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-(thiophen-3-yl)purine is classified as halogenated nucleosides (Formula C14H13FN4O3S; molecular weight 336.34).
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-(thiophen-3-yl)purine — Fluorinated, thienyl-substituted purine nucleoside building block for structure-specific nucleoside and oligonucleotide synthesis research.
For 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-(thiophen-3-yl)purine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- (2R,3S,4S,5R)-4-Fluoro-5-(hydroxymethyl)-2-(6-thiophen-3-ylpurin-9-yl)oxolan-3-ol
Useful catalog search terms
- CAS 1612191-90-8
- PubChem CID 156594202
Physicochemical data
| PubChem CID | 156594202 |
|---|---|
| InChIKey | JJUMGDXEERDGDF-ULSKOJAOSA-N |
| IUPAC name | (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(6-thiophen-3-ylpurin-9-yl)oxolan-3-ol |
| SMILES | C1=CSC=C1C2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)F)O |
| Sugar modification | 3'-deoxy-3'-fluoro |
| Purine substitution | 6-(thiophen-3-yl) |
| InChI | InChI=1S/C14H13FN4O3S/c15-9-8(3-20)22-14(12(9)21)19-6-18-11-10(7-1-2-23-4-7)16-5-17-13(11)19/h1-2,4-6,8-9,12,14,20-21H,3H2/t8-,9-,12-,14-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-(thiophen-3-yl)purine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-(thiophen-3-yl)purine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0047 and CAS 1612191-90-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.