2'-Fluoro Phosphoramidites
DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite
Quick view. An N2-dimethylformamidine-protected 2'-fluoro guanosine CE phosphoramidite building block for research-use oligonucleotide synthesis. CAS 3081868-42-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite is classified as protected 2'-fluoro guanosine ce phosphoramidite (Formula C43H52FN8O7P; molecular weight 842.91).
DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite — This protected CE phosphoramidite is cataloged as a guanosine building block for research-use oligonucleotide synthesis.
For DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-F-dG(dmf)-3'-CE-Phosphoramidite
- DMT-2'-F-dG(dmf)-phosphoramidite
- 5'-O-DMTr-2'-fluoro-N2-dimethylformamidine-guanosine-3'-CE phosphoramidite
Useful catalog search terms
- CAS 3081868-42-7
- C43H52FN8O7P
Physicochemical data
| Nucleobase protection | N2-dimethylformamidine (dmf) |
|---|---|
| 5' protection | 4,4'-Dimethoxytrityl (DMTr) |
| Sugar modification | 2'-fluoro |
| 3'-function | 2-cyanoethyl N,N-diisopropyl phosphoramidite |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2FP-0004DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite
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BX-2FP-0005DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite
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BX-2FP-0007DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite
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Frequently asked questions
Can the package size for DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0006 and CAS 3081868-42-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.