2'-Fluoro Phosphoramidites
DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite
Quick view. We supply DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite as a sterically constrained 2'-fluoro/2'-methyl uridine amidite for introducing noncanonical sugar geometry into oligonucleotides. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%.
Product profile
DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- DMT-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite
- DMTr-(2'R)-2'-F-2'-Me-dU-3'-2-cyanoethyl phosphoramidite
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- 2'-fluoro modification
- phosphoramidite coupling group
- 2'-Fluoro Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; 2'-fluoro modification; phosphoramidite coupling group |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 1528734-00-0
BX-2FP-0003DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0004DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0005DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0006DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 3081868-42-7
BX-2FP-0007DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 2227140-01-2
Frequently asked questions
Can the package size for DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0001, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry.