2'-O-MOE Phosphoramidites
DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite is an N4-benzoyl-protected 2'-O-(2-methoxyethyl) 5-methylcytidine building block for research-use oligonucleotide synthesis. CAS 163759-94-2. Catalog target purity: 99%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite is classified as protected 2'-o-moe 5-methylcytidine phosphoramidite (Formula C50H60N5O10P; molecular weight 922.00).
DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite — N4-benzoyl-protected 2'-O-(2-methoxyethyl) 5-methylcytidine phosphoramidite building block for research-use oligonucleotide synthesis.
For DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- 2'-O-MOE-5-Me-C(Bz) Phosphoramidite
- DMT-2'-O-MOE-5-Me-rC(Bz) Phosphoramidite
- N4-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine-3'-CE Phosphoramidite
Useful catalog search terms
- 163759-94-2
- PubChem 101234327
- C50H60N5O10P
- Thermo Fisher 27-1020-05
Physicochemical data
| Base protection | N4-benzoyl |
|---|---|
| Base modification | 5-methyl |
| Ribose modification | 2'-O-(2-methoxyethyl) |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | FLIGVMLIIDVDSN-GICDFOIUSA-N |
| InChI | InChI=1S/C50H60N5O10P/c1-34(2)55(35(3)4)66(63-29-15-28-51)65-44-43(33-62-50(38-18-13-10-14-19-38,39-20-24-41(59-7)25-21-39)40-22-26-42(60-8)27-23-40)64-48(45(44)61-31-30-58-6)54-32-36(5)46(53-49(54)57)52-47(56)37-16-11-9-12-17-37/h9-14,16-27,32,34-35,43-45,48H,15,29-31,33H2,1-8H3,(H,52,53,56,57)/t43-,44-,45-,48-,66?/m1/s1 |
| SMILES | CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCOC |
| PubChem CID | 101234327 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2OMP-0002DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite
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BX-2OMP-0003DMTr-2'-O-MOE-5-Me-rC(DMTr)-3'-CE-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: N/A
BX-2OMP-0004DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: 251647-56-0
BX-2OMP-0006DMTr-2'-O-MOE-rA(Bz)-3'-(1-hydroxy-N,N-diisopropyl)phosphoramidite
2'-O-MOE Phosphoramidites · CAS: N/A
BX-2OMP-0007DMTr-2'-O-MOE-rA(DMTr)-3'-CE-Phosphoramidite
2'-O-MOE Phosphoramidites · CAS: N/A
Frequently asked questions
Can the package size for DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMP-0081 and CAS 163759-94-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.