BX LAB PRODUCT CATEGORY
2'-O-MOE Phosphoramidites
Quick view. 2′-O-methoxyethyl phosphoramidites for modified RNA and antisense oligonucleotide process development. This category currently includes 22 products. 2'-O-MOE Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
Category guide
2'-O-MOE Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.
Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.
Product-family considerations
- Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
- Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
- Common ribose modifications can improve nuclease resistance and modulate RNA-like binding behavior.
- Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
- Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.
Category literature
These publications provide background for the 2'-O-MOE Phosphoramidites product family. Individual product pages only show additional product- or feature-relevant references.
Selection checklist
| Exact identity | Match the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable. |
|---|---|
| Specification | Define target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits. |
| Workflow fit | Share the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility. |
| Supply need | Provide initial quantity, expected future scale, packaging preference, timeline and documentation requirements. |
22 products
≥98.0% · CAS: 251647-53-7
BX-2OMP-0078DMTr-2'-O-MOE-rG(iBu)-3'-CE-Phosphoramidite≥98.0% · CAS: 251647-55-9
BX-2OMP-0079DMTr-2'-O-MOE-rT-3'-CE-Phosphoramidite≥98.0% · CAS: 163878-63-5
BX-2OMP-0080DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite99% · CAS: 163759-94-2
BX-2OMP-0081DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-Phosphoramidite≥98% · CAS: 2379296-21-4
BX-2OMP-0002DMTr-2'-O-MOE-rA-3'-CE-Phosphoramidite≥98% · CAS: 1558023-78-1
BX-2OMP-0008DMTr-2'-O-MOE-5-Me-rC(Ac)-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0001DMTr-2'-O-MOE-5-Me-rC(DMTr)-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0003DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite≥98% · CAS: 251647-56-0
BX-2OMP-0004DMTr-2'-O-MOE-rA(Bz)-3'-(1-hydroxy-N,N-diisopropyl)phosphoramidite≥98% · CAS: N/A
BX-2OMP-0006DMTr-2'-O-MOE-rA(DMTr)-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0007DMTr-2'-O-MOE-rC(Ac)-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0009DMTr-2'-O-MOE-rG(DMTr)-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0010DMTr-2'-O-MOE-rG(dmf)-3'-CE-Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0012DMTr-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0013DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite≥98% · CAS: 1558023-79-2
BX-2OMP-0014DMTr-2'-O-MOE-rC(Bz)-3'-CE-Phosphoramidite≥98% · CAS: 251647-54-8
BX-2OMP-0077DMT-2'-O-MOE-G(dmf)-CE Phosphoramidite≥98% · CAS: N/A
BX-2OMP-0063DMT-2'-O-MOE-I-CE Phosphoramidite≥97% · CAS: N/A
BX-2OMP-0064N2,N6-Diisobutyryl-5'-O-DMTr-2'-O-MOE-2,6-diaminopurine riboside 3'-CE phosphoramidite≥98% · CAS: N/A
BX-OP-0095N4-Acetyl-5-methyl-5'-O-DMTr-2'-O-MOE-cytidine-3'-CE phosphoramidite≥98% · CAS: N/A
BX-2OMP-00885'-O-DMTr-2'-O-(2-methoxyethyl)uridine-3'-CE phosphoramidite≥98% · CAS: 163759-97-5
BX-2OMP-0062Frequently asked questions
What are typical uses for 2'-O-MOE Phosphoramidites?
2'-O-MOE Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.
What should be confirmed before ordering 2'-O-MOE Phosphoramidites?
Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.
Are custom quantities or related analogs available?
BX Lab reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.
Need help selecting a product?
Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.