2'-O-MOE Phosphoramidites
DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite
Quick view. An unprotected-N2 2'-O-MOE guanosine CE phosphoramidite for research use in modified oligonucleotide synthesis. CAS 1558023-79-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite is classified as 2'-o-moe phosphoramidites (Formula C43H54N7O9P; molecular weight 843.92).
DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite — Unprotected-N2 2'-O-MOE guanosine building block for solid-phase oligonucleotide synthesis research.
For DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-O-MOE-rG-3'-CE-Phosphoramidite
- 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite)
Useful catalog search terms
- CAS 1558023-79-2
- C43H54N7O9P
- unprotected N2 2'-O-MOE guanosine phosphoramidite
Physicochemical data
| InChIKey | BONZQXQXGMLHEM-USUFPPIWSA-N |
|---|---|
| 2'-O modification | 2-methoxyethyl (MOE) |
| Base protection | N2 unprotected |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMP-0014 and CAS 1558023-79-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.