cEt-BNA
DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite
Quick view. We supply DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite as a constrained ethyl BNA/LNA-family cytidine amidite for high-affinity therapeutic oligonucleotide synthesis. A public CAS number is not assigned for this exact form. Catalog target purity: Specification on request.
Product profile
DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite, high-affinity monomers require careful positional design; over-substitution may increase off-target binding or complicate synthesis.
Names and search terms
Confirmed or normalized name variants
- DMT-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite
- DMTr-S-cEt-5-Me-rC(Ac)-3'-2-cyanoethyl phosphoramidite
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- conformationally locked sugar
- phosphoramidite coupling group
- cEt-BNA
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; conformationally locked sugar; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- Locked/bicyclic sugar motifs can substantially increase duplex thermal stability and mismatch discrimination.
Method limitations
- High-affinity monomers require careful positional design; over-substitution may increase off-target binding or complicate synthesis.
These points describe DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
DMTr-S-cEt-5-Me-rC(Bz)-3'-CE-Phosphoramidite
cEt-BNA · CAS: 1197033-17-2
BX-CB-0003DMTr-S-cEt-rG(iBu)-3'-CE-Phosphoramidite
cEt-BNA · CAS: 945628-66-0
BX-CB-0004DMTr-S-cEt-rA(Bz)-3'-CE-Phosphoramidite
cEt-BNA · CAS: 1197033-19-4
BX-CB-0005S-cEt-T-CE-Phosphoramidite
cEt-BNA · CAS: 1197033-22-9
BX-CB-0006BNA(N-Me)-A(Bz)-CE-Phosphoramidite
cEt-BNA · CAS: 1247023-38-6
BX-CB-0007BNA(N-Me)-G(dmf)-CE-Phosphoramidite
cEt-BNA · CAS: N/A
Frequently asked questions
Can the package size for DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CB-0001, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss DMTr-S-cEt-5-Me-rC(Ac)-3'-CE-Phosphoramidite or the named structural feature represented by this product.