Modified Nucleotides
Guanosine 3', 5'-cyclic-monophosphate, free acid
Quick view. We supply Guanosine 3', 5'-cyclic-monophosphate, free acid as a modified nucleotide for nucleic acid chemistry, enzymology and analytical reference workflows. CAS 7665-99-8. Catalog target purity: Specification on request.
Product profile
Guanosine 3', 5'-cyclic-monophosphate, free acid is classified as nucleotide or nucleotide analog (Formula C10H12N5O7P; molecular weight 345.21).
Guanosine 3', 5'-cyclic-monophosphate, free acid can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For Guanosine 3', 5'-cyclic-monophosphate, free acid, reported solubility: 1% sodium bicarbonate: 50 mg/mL. Storage: -20°C.
Names and search terms
Confirmed or normalized name variants
- guanosine cyclic 3',5'-phosphate
- CGMP
- 3:5-CGMP
- cyclicgmp
- 3',5'-cGMPH
- 3',5'-cyclic GMP
- cGMP, cyclic GMP
- Cyclic 3',5'-guanylic acid
Useful catalog search terms
- CAS 7665-99-8
- Nucleotide or nucleotide analog
- Modified Nucleotides
Physicochemical data
| InChI | InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s |
|---|---|
| InChIKey | ZOOGRGPOEVQQDX-UUOKFMHZSA-N |
| SMILES | O=C1N=C(NC2=C1N=CN2[C@@H]1O[C@]2([H])COP(O[C@@]2([H])[C@H]1O)(O)=O)N |
| Melting point | >242°C (dec.) |
| pKa | 1.03±0.60(Predicted) |
| Form | powder |
| Color | white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
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Frequently asked questions
Can the package size for Guanosine 3', 5'-cyclic-monophosphate, free acid be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MODN-0219 and CAS 7665-99-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleotides product family and its named chemistry.