Amino-modified Nucleosides
3-(3-Amino-3-carboxypropyl)-1-methylpseudouridine
Quick view. 3-(3-Amino-3-carboxypropyl)-1-methylpseudouridine is an aminocarboxypropyl-modified pseudouridine, commonly abbreviated m1acp3-Psi, for research workflows that specify this modified nucleoside. CAS 52777-29-4. Catalog target purity: ≥99%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3-(3-Amino-3-carboxypropyl)-1-methylpseudouridine is classified as aminocarboxypropyl-modified pseudouridine (Formula C14H21N3O8; molecular weight 359.33).
3-(3-Amino-3-carboxypropyl)-1-methylpseudouridine — Modified nucleoside reference for research workflows studying or measuring m1acp3-Psi.
For 3-(3-Amino-3-carboxypropyl)-1-methylpseudouridine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- N1-Methyl-N3-(3-amino-3-carboxypropyl)pseudouridine
- m1acp3-Psi
- ACPMPSU
Useful catalog search terms
- CAS 52777-29-4
Physicochemical data
| Common notation | m1acp3-Psi |
|---|---|
| InChIKey | CTPQMQZKRWLMRA-LYTXVXJPSA-N |
| PubChem CID | 193882 |
| Stereochemistry boundary | Ribose configuration defined; amino-bearing side-chain center unspecified |
| InChI | InChI=1S/C14H21N3O8/c1-16-4-6(11-10(20)9(19)8(5-18)25-11)12(21)17(14(16)24)3-2-7(15)13(22)23/h4,7-11,18-20H,2-3,5,15H2,1H3,(H,22,23)/t7?,8-,9-,10-,11+/m1/s1 |
| SMILES | CN1C=C(C(=O)N(C1=O)CCC(C(=O)O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
These points describe 3-(3-Amino-3-carboxypropyl)-1-methylpseudouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3-(3-Amino-3-carboxypropyl)-1-methylpseudouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0125 and CAS 52777-29-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.