Modified Nucleosides
N1-Methylinosine
Quick view. We supply N1-Methylinosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2140-73-0. Catalog target purity: Specification on request.
Product profile
N1-Methylinosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H14N4O5; molecular weight 282.25).
N1-Methylinosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N1-Methylinosine, reported solubility: Soluble in DMSO; confirm lot-specific concentration limits. Storage: −20 °C.
Names and search terms
Confirmed or normalized name variants
- 1-methylinosine
- Inosine, 1-methyl
- RNA-modified nucleoside m1I
- WJNGQIYEQLPJMN-LEIICMHDSA-N
Useful catalog search terms
- CAS 2140-73-0
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| Melting point | 211–212 °C |
|---|---|
| SMILES | CN1C=NC2=C(C1=O)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O |
| Identity note | CAS and structure correspond to N1-methylinosine (m1I); confirm hydration and salt form on the current specification. |
| InChI | InChI=1/C11H16N4O5/c1-14-3-13-9-6(10(14)19)12-4-15(9)11-8(18)7(17)5(2-16)20-11/h4-5,7-8,11,16-19H,2-3H2,1H3/t5-,7-,8-,11-/s |
| InChIKey | QCTGLUIBIHRABQ-ABFAXUGDNA-N |
| Boiling point | 695.3±65.0 °C(Predicted) |
| Density | 1.88±0.1 g/cm3(Predicted) |
| pKa | 13.22±0.70(Predicted) |
| Form | A solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for N1-Methylinosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0744 and CAS 2140-73-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.