Halogenated Nucleosides
N2-Isobutyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine
Quick view. Protected guanosine derivative bearing N2-isobutyroyl, 5'-O-DMT, and 3'-deoxy-3'-fluoro features. CAS 2080404-19-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N2-Isobutyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is classified as halogenated nucleosides (Formula C35H36FN5O7; molecular weight 657.70 g/mol).
N2-Isobutyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For N2-Isobutyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 2080404-19-7
Physicochemical data
| Nucleoside scaffold | guanosine |
|---|---|
| Base protection | N2-isobutyroyl |
| 5' protection | DMT |
| Sugar modification | 3'-deoxy-3'-fluoro |
| InChIKey | DHDSAIMYCCHNMS-UNVYQVKTSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N2-Isobutyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N2-Isobutyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0194 and CAS 2080404-19-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.