Modified Nucleosides
N2-Isobutyryl-3'-O-methylguanosine
Quick view. An N2-isobutyryl-protected 3'-O-methylguanosine building block for structure-specific modified-nucleoside and nucleotide synthesis research. CAS 160107-07-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N2-Isobutyryl-3'-O-methylguanosine is classified as modified nucleosides (Formula C15H21N5O6; molecular weight 367.36).
N2-Isobutyryl-3'-O-methylguanosine — N2-isobutyryl-protected 3'-O-methylguanosine building block for structure-specific modified-nucleoside and nucleotide synthesis research.
For N2-Isobutyryl-3'-O-methylguanosine, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- N2-iso-Butyroyl-3'-O-methylguanosine
Useful catalog search terms
- CAS 160107-07-3
- PubChem CID 145710473
Physicochemical data
| PubChem CID | 145710473 |
|---|---|
| InChIKey | WKXJLMCHKRMCEY-AKAIJSEGSA-N |
| IUPAC name | N-[9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide |
| SMILES | CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)OC)O |
| Nucleobase protection | N2-isobutyryl |
| Sugar modification | 3'-O-methyl |
| InChI | InChI=1S/C15H21N5O6/c1-6(2)12(23)18-15-17-11-8(13(24)19-15)16-5-20(11)14-9(22)10(25-3)7(4-21)26-14/h5-7,9-10,14,21-22H,4H2,1-3H3,(H2,17,18,19,23,24)/t7-,9-,10-,14-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe N2-Isobutyryl-3'-O-methylguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N2-Isobutyryl-3'-O-methylguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0786 and CAS 160107-07-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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