Protected Nucleosides
N2-Isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine
Quick view. We supply N2-Isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine as a protected dideoxy nucleoside intermediate for chain-terminator, analog and modified nucleotide synthesis. CAS 119794-40-0. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
N2-Isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine is classified as nucleoside or protected nucleoside intermediate.
N2-Isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N2-Isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Useful catalog search terms
- CAS 119794-40-0
- Nucleoside or protected nucleoside intermediate
- Protected Nucleosides
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe N2-Isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N2-Isobutyryl-2',3'-didehydro-2',3'-dideoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0132 and CAS 119794-40-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.