Protected Nucleosides
N2-Isobutyryl-2',3'-dideoxyguanosine
Quick view. An N2-isobutyryl-protected 2',3'-dideoxyguanosine derivative, identified by CAS 85326-13-2. CAS 85326-13-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N2-Isobutyryl-2',3'-dideoxyguanosine is classified as protected nucleosides (Formula C14H19N5O4; molecular weight 321.33 g/mol).
N2-Isobutyryl-2',3'-dideoxyguanosine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For N2-Isobutyryl-2',3'-dideoxyguanosine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Useful catalog search terms
- CAS 85326-13-2
Physicochemical data
| Nucleoside scaffold | 2',3'-dideoxyguanosine |
|---|---|
| Base protection | N2-isobutyryl |
| Free hydroxyl | 5'-OH |
| PubChem CID | 136177453 |
| SMILES | CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3CC[C@H](O3)CO |
| InChI | InChI=1S/C14H19N5O4/c1-7(2)12(21)17-14-16-11-10(13(22)18-14)15-6-19(11)9-4-3-8(5-20)23-9/h6-9,20H,3-5H2,1-2H3,(H2,16,17,18,21,22)/t8-,9+/m0/s1 |
| InChIKey | VFNSWNMQOZPXBE-DTWKUNHWSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe N2-Isobutyryl-2',3'-dideoxyguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N2-Isobutyryl-2',3'-dideoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0298 and CAS 85326-13-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.