Modified Nucleosides
N2,N2-Dimethylguanosine
Quick view. We supply N2,N2-Dimethylguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 2140-67-2. Catalog target purity: Specification on request.
Product profile
N2,N2-Dimethylguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C12H17N5O5; molecular weight 311.29).
N2,N2-Dimethylguanosine — 2-(Dimethylamino)guanosine (cas# 2140-67-2) is a compound useful in organic synthesis.
For N2,N2-Dimethylguanosine, reported solubility: Aqueous Base (Sparingly), DMSO (Slightly), Methanol (Slightly), Water (Slightly,. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- m,2G
- M(2/2) GUO
- 2-(DIMETHYLAMINO)GUA
- N,N-Dimethylguanosine
- 2,2-DiMethylguanosine
- 2-(DIMETHYLAMINO)GUANOSINE
- 2-Dimethylamino-D-guanosine
- N(sup 2),N(sup 2)-dimethylguanosine
Useful catalog search terms
- CAS 2140-67-2
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C12H17N5O5/c1-16(2)12-14-9-6(10(21)15-12)13-4-17(9)11-8(20)7(19)5(3-18)22-11/h4-5,7-8,11,18-20H,3H2,1-2H3,(H,14,15,21)/t5-,7-,8-,11-/m1/s |
|---|---|
| InChIKey | RSPURTUNRHNVGF-IOSLPCCCSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N(C)C)=O)N=C2)[C@H](O)[C@@H]1O |
| Melting point | 249-251°C |
| Density | 1.83±0.1 g/cm3(Predicted) |
| pKa | 9.63±0.20(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- N2,N2-Dimethylguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for N2,N2-Dimethylguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0373 and CAS 2140-67-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.