Modified Nucleosides
N3-Methylthymidine
Quick view. We supply N3-Methylthymidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 958-74-7. Catalog target purity: Specification on request.
Product profile
N3-Methylthymidine is classified as nucleoside or protected nucleoside intermediate (Formula C11H16N2O5; molecular weight 256.26).
N3-Methylthymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N3-Methylthymidine, reported solubility: DMSO (Slightly), Methanol (Slightly). Storage: ?20°C.
Names and search terms
Confirmed or normalized name variants
- 3-methylthymidine
- methylthymidine
- 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,5-dimethylpyrimidine-2,4-dione
Useful catalog search terms
- CAS 958-74-7
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C11H16N2O5/c1-6-4-13(11(17)12(2)10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,3,5H2,1-2H3/t7-,8+,9+/m0/s |
|---|---|
| InChIKey | JCVDICFLPGDHAT-DJLDLDEBSA-N |
| SMILES | CC1=CN(C(=O)N(C1=O)C)[C@H]2C[C@@H]([C@H](O2)CO)O |
| Melting point | 130-133°C |
| Boiling point | 457.7±55.0 °C(Predicted) |
| Density | 1.409±0.06 g/cm3(Predicted) |
| pKa | 13.89±0.60(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for N3-Methylthymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0718 and CAS 958-74-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.