Protected Nucleosides
N4-Benzoyl-2'-O,4'-C-[(S)-ethylidene]-5-methylcytidine
Quick view. We supply N4-Benzoyl-2'-O,4'-C-[(S)-ethylidene]-5-methylcytidine as a protected locked-nucleic-acid nucleoside intermediate for high-affinity oligonucleotide monomer synthesis. CAS 1197033-12-7. Catalog target purity: Specification on request.
![Chemical structure of N4-Benzoyl-2'-O,4'-C-[(S)-ethylidene]-5-methylcytidine](/structures/68e4b20cd68749aa.svg)
Product profile
N4-Benzoyl-2'-O,4'-C-[(S)-ethylidene]-5-methylcytidine is classified as nucleoside or protected nucleoside intermediate (Formula C19H19N5O5; molecular weight 397.38).
N4-Benzoyl-2'-O,4'-C-[(S)-ethylidene]-5-methylcytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For N4-Benzoyl-2'-O,4'-C-[(S)-ethylidene]-5-methylcytidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 9-[2,5-Anhydro-6-deoxy-4-(hydroxymethyl)-alpha-L-mannofuranosyl]-N-benzoyl-9H-purin-6-amine
Useful catalog search terms
- CAS 1197033-12-7
- Nucleoside or protected nucleoside intermediate
- Protected Nucleosides
Physicochemical data
| InChI | InChI=1S/C19H19N5O5/c1-10-19(7-25)14(26)13(28-10)18(29-19)24-9-22-12-15(20-8-21-16(12)24)23-17(27)11-5-3-2-4-6-11/h2-6,8-10,13-14,18,25-26H,7H2,1H3,(H,20,21,23,27)/t10-,13+,14-,18+,19-/m0/s |
|---|---|
| InChIKey | LDDFACWXKZYSFU-DZSXKSNSSA-N |
| SMILES | C[C@H]1[C@]2([C@H]([C@@H](O1)[C@@H](O2)N3C=NC4=C(N=CN=C43)NC(=O)C5=CC=CC=C5)O)CO |
| Density | 1.69±0.1 g/cm3(Predicted) |
| pKa | 13.02±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for N4-Benzoyl-2'-O,4'-C-[(S)-ethylidene]-5-methylcytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0131 and CAS 1197033-12-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.