Protected Nucleosides
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylcytidine
Quick view. A protected cytidine derivative bearing N4-benzoyl, 5'-O-(4,4'-dimethoxytrityl) and 3'-O-methyl substituents, CAS 138906-83-9. CAS 138906-83-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylcytidine is classified as protected nucleosides (Formula C38H37N3O8; molecular weight 663.72).
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylcytidine can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylcytidine, the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methylcytidine
Useful catalog search terms
- CAS 138906-83-9
Physicochemical data
| Base protection | N4-Benzoyl |
|---|---|
| 5'-hydroxyl protection | DMTr |
| 3'-hydroxyl substitution | O-Methyl |
| Product form | Protected nucleoside (not phosphoramidite) |
| PubChem CID | 175676705 |
| InChI | InChI=1S/C38H37N3O8/c1-45-29-18-14-27(15-19-29)38(26-12-8-5-9-13-26,28-16-20-30(46-2)21-17-28)48-24-31-34(47-3)33(42)36(49-31)41-23-22-32(40-37(41)44)39-35(43)25-10-6-4-7-11-25/h4-23,31,33-34,36,42H,24H2,1-3H3,(H,39,40,43,44)/t31-,33-,34-,36-/m1/s1 |
| InChIKey | PDEJBMOJZNVHAB-YDXJMRNDSA-N |
| SMILES | CO[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylcytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylcytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0361 and CAS 138906-83-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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