Halogenated Nucleosides
N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine
Quick view. A protected adenosine intermediate bearing N6-benzoyl, 3'-deoxy-3'-fluoro and 5'-O-DMTr substitution for structure-specific synthesis research. CAS 170871-87-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine is classified as halogenated nucleosides (Formula C38H34FN5O6; molecular weight 675.72).
N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine — Protected 3'-fluoro-3'-deoxyadenosine intermediate for structure-specific modified-nucleoside and nucleotide synthesis research.
For N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- N6-Benzoyl-3'-deoxy-5'-O-DMTr-3'-fluoroadenosine
- Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-3'-fluoro-
Useful catalog search terms
- CAS 170871-87-1
- N6-benzoyl 3-fluoro DMTr adenosine
Physicochemical data
| Nucleobase protection | N6-Benzoyl |
|---|---|
| Sugar modification | 3'-Deoxy-3'-fluoro |
| 5' protection | 4,4'-Dimethoxytrityl (DMTr) |
| Free hydroxyl | 2'-OH |
| PubChem CID | 129081131 |
| InChI | InChI=1S/C38H34FN5O6/c1-47-28-17-13-26(14-18-28)38(25-11-7-4-8-12-25,27-15-19-29(48-2)20-16-27)49-21-30-31(39)33(45)37(50-30)44-23-42-32-34(40-22-41-35(32)44)43-36(46)24-9-5-3-6-10-24/h3-20,22-23,30-31,33,37,45H,21H2,1-2H3,(H,40,41,43,46)/t30-,31-,33-,37-/m1/s1 |
| InChIKey | TVVPSEDSHAQKKZ-VYUOYPLNSA-N |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N6-Benzoyl-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluoroadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0177 and CAS 170871-87-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.