Amino-modified Nucleosides
N6-Dimethylaminomethylidene-2'-deoxyisoguanosine
Quick view. An N6-dimethylaminomethylidene-protected 2'-deoxyisoguanosine derivative, CAS 146196-17-0, with formula C13H18N6O4. CAS 146196-17-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N6-Dimethylaminomethylidene-2'-deoxyisoguanosine is classified as amino-modified nucleosides (Formula C13H18N6O4; molecular weight 322.32).
N6-Dimethylaminomethylidene-2'-deoxyisoguanosine — An N6-dimethylaminomethylidene-protected 2'-deoxyisoguanosine intermediate for research use in modified nucleoside synthesis.
For N6-Dimethylaminomethylidene-2'-deoxyisoguanosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- N'-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1H-purin-6-yl]-N,N-dimethylmethanimidamide
Useful catalog search terms
- 146196-17-0
- PubChem CID 102067084
- N6 protected 2'-deoxyisoguanosine
Physicochemical data
| PubChem CID | 102067084 |
|---|---|
| Nucleoside class | 2'-Deoxyisoguanosine derivative |
| Exocyclic amine protection | N6-Dimethylaminomethylidene |
| Sugar configuration | Beta-D-2'-deoxyribofuranosyl |
| Hydroxyl state | Free 3' and 5' hydroxyls |
| Amidine geometry | Not specified |
| Physical form | Solid (external record; not a BX batch specification) |
| InChI | InChI=1S/C13H18N6O4/c1-18(2)5-15-11-10-12(17-13(22)16-11)19(6-14-10)9-3-7(21)8(4-20)23-9/h5-9,20-21H,3-4H2,1-2H3,(H,16,17,22)/t7-,8+,9+/m0/s1 |
| InChIKey | FOSUWRSEKRWMFJ-DJLDLDEBSA-N |
| SMILES | CN(C)C=NC1=C2C(=NC(=O)N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe N6-Dimethylaminomethylidene-2'-deoxyisoguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for N6-Dimethylaminomethylidene-2'-deoxyisoguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0027 and CAS 146196-17-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.