2'-FANA Nucleosides
2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine
Quick view. We supply 2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 78636-53-0. Catalog target purity: Specification on request.
Product profile
2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14FN3O4; molecular weight 259.23).
2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 1-(2-Deoxy-2-fluoropentofuranosyl)-4-imino-5-methyl-1,4-dihydropyrimidin-2-ol
- 2'-fluoro-5-methylarabino-furanosylcytosine
- 2'-Deoxy-2'-fluoro-5-methyl-araobinocytidine
- 2'-Deoxy-2'-fluoro-5-Methyl-beta-D-arabinocytidine
- 2’-Deoxy-2’-fluoro-5-methyl-arabinocytidine, Anticancer agent
- 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl
- 4-Amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-2(1H)-pyrimidinone
Useful catalog search terms
- CAS 78636-53-0
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- 2'-FANA Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification |
|---|---|
| InChI | InChI=1S/C10H14FN3O4/c1-4-2-14(10(17)13-8(4)12)9-6(11)7(16)5(3-15)18-9/h,5-7,9,15-16H,3H2,1H3,(H2,12,13,17)/t5-,6+,7-,9+/m1/s |
| InChIKey | QZZJZXAWLQYJFK-AYHNYZOXSA-N |
| SMILES | CC1=CN(C(=O)N=C1N)[C@@H]2[C@H]([C@@H]([C@H](O2)CO)O)F |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FAN-0077 and CAS 78636-53-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine or the named structural feature represented by this product.