Protected Nucleosides
3'-O-Acetylthymidine
Quick view. We supply 3'-O-Acetylthymidine as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 21090-30-2. Catalog target purity: Specification on request.
Product profile
3'-O-Acetylthymidine is classified as nucleoside or protected nucleoside intermediate (Formula C12H16N2O6; molecular weight 284.27).
3'-O-Acetylthymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-O-Acetylthymidine, storage: Store at 0-5°C.
Names and search terms
Confirmed or normalized name variants
- 1-(3-O-Acetyl-2-deoxypentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
- 3'-ACETYLTHYMIDINE
- 3'-acetatethyMidine
- Thymidine 3'-acetate
- 3'-O-acetyl-2'-deoxythyMidine
Useful catalog search terms
- CAS 21090-30-2
- Nucleoside or protected nucleoside intermediate
- Protected Nucleosides
Physicochemical data
| InChI | InChI=1S/C12H16N2O6/c1-6-4-14(12(18)13-11(6)17)10-3-8(19-7(2)16)9(5-15)20-10/h4,8-10,15H,3,5H2,1-2H3,(H,13,17,18) |
|---|---|
| InChIKey | IRFKBRPHBYCMQU-UHFFFAOYSA-N |
| SMILES | CC(=O)OC1CC(n2cc(C)c(O)nc2=O)OC1CO |
| Melting point | 174 °C |
| Density | 1.42±0.1 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 3'-O-Acetylthymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0197 and CAS 21090-30-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.