Base-protected Nucleosides
2',3'-dideoxy-C(Bz)
Quick view. 2',3'-dideoxy-C(Bz) is N4-benzoyl-2',3'-dideoxycytidine with a free 5'-hydroxyl and defined (2R,5S) sugar stereochemistry. CAS 120885-60-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-dideoxy-C(Bz) is classified as base-protected nucleosides (Formula C16H17N3O4; molecular weight 315.32).
2',3'-dideoxy-C(Bz) — Protected dideoxycytidine intermediate for research route development where the 5'-hydroxyl remains available for subsequent transformation.
For 2',3'-dideoxy-C(Bz), polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- N4-benzoyl-2',3'-dideoxycytidine
Useful catalog search terms
- CAS 120885-60-1
Physicochemical data
| Base protection | N4-benzoyl |
|---|---|
| Sugar substitution | 2',3'-dideoxy |
| Unprotected position | 5'-hydroxyl |
| Sugar stereochemistry | (2R,5S) |
| Systematic name | N-[1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide |
| InChIKey | YGZQYMMFALYKCO-GXTWGEPZSA-N |
| InChI | InChI=1S/C16H17N3O4/c20-10-12-6-7-14(23-12)19-9-8-13(18-16(19)22)17-15(21)11-4-2-1-3-5-11/h1-5,8-9,12,14,20H,6-7,10H2,(H,17,18,21,22)/t12-,14+/m0/s1 |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-dideoxy-C(Bz) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-dideoxy-C(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0003 and CAS 120885-60-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.