Base-protected Nucleosides
2'-F-dG(DMF)
Quick view. N2-dimethylformamidine-protected 2'-fluoro-2'-deoxyguanosine with free 3' and 5' hydroxyl groups. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-F-dG(DMF) is classified as base-protected nucleosides.
2'-F-dG(DMF) is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 2'-F-dG(DMF), coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- N2-Dimethylformamidine-2'-fluoro-2'-deoxyguanosine
- 2'-Fluoro-dG(dmf)
Physicochemical data
| Nucleoside scaffold | 2'-Fluoro-2'-deoxyguanosine |
|---|---|
| Nucleobase protection | N2-dimethylformamidine (dmf) |
| Hydroxyl state | 3' and 5' hydroxyl groups unprotected |
| CAS status | No public CAS assigned in the reviewed source set |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-F-dG(DMF) or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2',3'-dideoxy-C(Ac)
Base-protected Nucleosides · CAS: 119818-52-9
BX-PN-00032',3'-dideoxy-C(Bz)
Base-protected Nucleosides · CAS: 120885-60-1
BX-PN-00062'-O-4'-C-Locked-5-Me-rC(Bz)
Base-protected Nucleosides · CAS: 206055-81-4
BX-PN-00072'-O-4'-C-Locked-rC(Bz)
Base-protected Nucleosides · CAS: 221229-74-9
BX-PN-00092'-O-4'-C-Locked-rG(iBu)
Base-protected Nucleosides · CAS: 206055-68-7
BX-PN-00213'-O-carbamoyl-2'-dC(Bz)
Base-protected Nucleosides · CAS: N/A
Frequently asked questions
Can the package size for 2'-F-dG(DMF) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0005, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.