2'-Fluoro Phosphoramidites
2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite
Quick view. A protected 2'-fluoro-2'-deoxyinosine phosphoramidite bearing a 5'-DMTr group and a 3'-cyanoethyl N,N-diisopropylphosphoramidite group. CAS 2245842-16-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite is classified as 2'-fluoro phosphoramidites (Formula C40H46FN6O7P; molecular weight 772.80).
2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite — Identity-defined protected 2'-fluoro-2'-deoxyinosine CE phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For 2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-F-dI phosphoramidite
- 2'-fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE phosphoramidite
- 5'-O-DMTr-2'-fluoro-2'-deoxyinosine-3'-CED phosphoramidite
Useful catalog search terms
- 2'-fluoro-dI CE phosphoramidite
- CAS 2245842-16-2
Physicochemical data
| Nucleoside | 2'-Fluoro-2'-deoxyinosine |
|---|---|
| Sugar modification | 2'-Fluoro, 2'-deoxy |
| 5' protection | DMTr |
| 3'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| Base protection | None indicated |
| PubChem CID | 136240748 |
| InChI | InChI=1S/C40H46FN6O7P/c1-26(2)47(27(3)4)55(52-22-10-21-42)54-36-33(53-39(34(36)41)46-25-45-35-37(46)43-24-44-38(35)48)23-51-40(28-11-8-7-9-12-28,29-13-17-31(49-5)18-14-29)30-15-19-32(50-6)20-16-30/h7-9,11-20,24-27,33-34,36,39H,10,22-23H2,1-6H3,(H,43,44,48)/t33-,34-,36-,39-,55?/m1/s1 |
| InChIKey | GNQYQPLUWSYXRR-YRGZVQMCSA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1F)N2C=NC3=C2N=CNC3=O)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2FP-0003DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite
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BX-2FP-0004DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite
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BX-2FP-0005DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite
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BX-2FP-0006DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 3081868-42-7
Frequently asked questions
Can the package size for 2'-Fluoro-5'-O-DMTr-2'-deoxyinosine-3'-CE phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0021 and CAS 2245842-16-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.