2'-Fluoro Phosphoramidites
N4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite
Quick view. An N4-benzoyl- and 5'-O-DMTr-protected 2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite, CAS 182495-83-6. CAS 182495-83-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
N4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite is classified as 2'-fluoro phosphoramidites (Formula C47H53FN5O8P; molecular weight 865.94).
N4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For N4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-Fluoro-5MeC(Bz)-3'-phosphoramidite
- DMT-2'-F-dC(Bz)-CE-Phosphoramidite
- N-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite
Useful catalog search terms
- CAS 182495-83-6
- C47H53FN5O8P
- MFCD34548945
- XYPAFCMPDQWTME-LVTIEWELSA-N
Physicochemical data
| Nucleobase | N4-Benzoyl-5-methylcytosine |
|---|---|
| Sugar modification | 2'-Deoxy-2'-fluoro |
| 5' protection | DMTr |
| 3'-functionality | 2-Cyanoethyl N,N-diisopropyl phosphoramidite |
| Stereochemistry | Sugar assigned; phosphorus unspecified |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe N4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2FP-0002DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite
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BX-2FP-0003DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite
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BX-2FP-0004DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0005DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0006DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 3081868-42-7
Frequently asked questions
Can the package size for N4-Benzoyl-5'-O-DMTr-2'-deoxy-2'-fluoro-5-methylcytidine 3'-CE phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0032 and CAS 182495-83-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.