Other Phosphoramidites
3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite
Quick view. We supply 3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite as a specialty phosphoramidite for nonstandard oligonucleotide modification. CAS 129015-63-0. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C12H5Cl3F3N5O4; molecular weight 446.55).
3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For 3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- CAS 129015-63-0
- Protected oligonucleotide phosphoramidite building block
- phosphoramidite coupling group
- Other Phosphoramidites
Physicochemical data
| Key chemistry motifs | phosphoramidite coupling group |
|---|---|
| Boiling point | 405.7±55.0 °C(Predicted) |
| Density | 1.89±0.1 g/cm3(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 3’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-3’-fluoro uridine-2’-CED-phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0159 and CAS 129015-63-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Other Phosphoramidites product family and its named chemistry.