DMTr-protected Nucleosides
5'-O-DMTr-2'-O-(2-aminoethyl)-5-Me-rU
Quick view. 5'-O-DMTr-protected 5-methyluridine bearing a 2'-O-(2-aminoethyl) substituent and a free 3'-hydroxyl. CAS 242147-79-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5'-O-DMTr-2'-O-(2-aminoethyl)-5-Me-rU is classified as dmtr-protected nucleosides (Formula C33H37N3O8; molecular weight 603.66).
5'-O-DMTr-2'-O-(2-aminoethyl)-5-Me-rU provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 5'-O-DMTr-2'-O-(2-aminoethyl)-5-Me-rU, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2'-O-(2-aminoethyl)-5'-O-DMTr-5-methyluridine
- DMTr-2'-O-(2-aminoethyl)-5-Me-rU
Useful catalog search terms
- CAS 242147-79-1
Physicochemical data
| Nucleoside | 5-methyluridine |
|---|---|
| Hydroxyl protection | 5'-O-DMTr |
| 2' substituent | 2'-O-(2-aminoethyl) |
| Hydroxyl state | 3' hydroxyl group unprotected |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-O-DMTr-2'-O-(2-aminoethyl)-5-Me-rU or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-O-DMTr-2'-O-(2-aminoethyl)-5-Me-rU be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0027 and CAS 242147-79-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.