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BX LAB PRODUCT CATEGORY

DMTr-protected Nucleosides

Quick view. DMTr-protected nucleosides for selective 5′-hydroxyl handling and phosphoramidite or succinate preparation. This category currently includes 46 products. DMTr-protected Nucleosides products serve as starting materials, protected intermediates and analytical comparators in nucleoside, nucleotide and oligonucleotide chemistry.

Products46
Use scopeResearch use only
Pack sizeCustomized to requirements
SupportSelection and custom synthesis review

Category guide

Typical use

DMTr-protected Nucleosides products serve as starting materials, protected intermediates and analytical comparators in nucleoside, nucleotide and oligonucleotide chemistry.

How to select

Confirm anomeric and sugar stereochemistry, base identity, substitution position, protecting-group pattern and required downstream transformation.

How to qualify

Use orthogonal identity data such as NMR and MS together with chromatographic purity, water or residual-solvent review and route-specific impurity controls.

Product-family considerations

Common advantages
  • Nucleoside catalogs provide flexible entry points for protecting-group, phosphorylation and glycosylation-route development.
  • Availability of related analogs helps researchers compare base, sugar and substitution effects systematically.
Common limitations
  • Downstream use often requires additional protection, activation or purification before incorporation into oligonucleotide workflows.
  • Isomeric purity, water content and residual solvents should be matched to the planned chemistry.

Category literature

These publications provide background for the DMTr-protected Nucleosides product family. Individual product pages only show additional product- or feature-relevant references.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

46 products

3'-O-DMTr-2'-O-Me-rG(iBu)

Specification on request · CAS: N/A

BX-PN-0018
3'-O-DMTr-2'-O-Me-rU

Specification on request · CAS: N/A

BX-PN-0019
3'-O-DMTr-dA(Bz)

≥95% · CAS: 140712-79-4

BX-PN-0020
5'-O-DMTr-2'-F-dC(Bz)

Specification on request · CAS: N/A

BX-PN-0026
5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU

≥95% · CAS: 242147-79-1

BX-PN-0027
5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rA(Ac)

≥98% · CAS: 863408-41-7

BX-PN-0028
5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rC(Ac)

≥98% · CAS: 863408-42-8

BX-PN-0029
5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rG(Pac)

≥98% · CAS: 863408-43-9

BX-PN-0030
5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rU

Specification on request · CAS: 863408-40-6

BX-PN-0031
5'-O-DMTr-2'-O-4'-C-Locked-5-Me-rC(Bz)

≥95% · CAS: 445012-77-1

BX-PN-0032
5'-O-DMTr-2'-O-4'-C-Locked-5-Me-rU

≥95% · CAS: 206055-71-2

BX-PN-0033
5'-O-DMTr-2'-O-4'-C-Locked-rA(Bz)

≥98% · CAS: 206055-74-5

BX-PN-0034
5'-O-DMTr-2'-O-4'-C-Locked-rG(dmf)

≥95% · CAS: 709641-78-1

BX-PN-0035
5'-O-DMTr-2'-O-4'-C-Locked-rG(iBu)

Specification on request · CAS: 206055-72-3

BX-PN-0036
5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)

≥95% · CAS: 182496-01-1

BX-PN-0037
5'-O-DMTr-2'-O-MOE-5-Me-rU

≥95% · CAS: 163759-50-0

BX-PN-0038
5'-O-DMTr-2'-O-MOE-rA(Bz)

≥98% · CAS: 251647-48-0

BX-PN-0039
5'-O-DMTr-2'-O-MOE-rG(iBu)

≥97% · CAS: 251647-50-4

BX-PN-0040
5'-O-DMTr-2'-O-Me-rC(Bz)

≥98% · CAS: 110764-74-4

BX-PN-0041
5'-O-DMTr-2'-O-TBDMS-rA(Bz)

≥95% · CAS: 81265-93-2

BX-PN-0042
5'-O-DMTr-2'-O-TBDMS-rC(Bz)

≥98% · CAS: 81256-87-3

BX-PN-0044
5'-O-DMTr-2'-O-TBDMS-rG(iBu)

≥95% · CAS: 81279-39-2

BX-PN-0045
5'-O-DMTr-2'-O-TBDMS-rU

≥97% · CAS: 81246-80-2

BX-PN-0046
5'-O-DMTr-2'-O-TOM-rA(Ac)

Specification on request · CAS: 253586-22-0

BX-PN-0047
5'-O-DMTr-2'-O-TOM-rA(Bz)

≥98% · CAS: N/A

BX-PN-0048
5'-O-DMTr-2'-dA(Bz)

≥95% · CAS: 64325-78-6

BX-PN-0049
5'-O-DMTr-2'-dC(Ac)

≥96% · CAS: 100898-63-3

BX-PN-0050
5'-O-DMTr-2'-dG(iBu)

≥97% · CAS: 68892-41-1

BX-PN-0051
5'-O-DMTr-2'-dT

≥95% · CAS: 40615-39-2

BX-PN-0052
5'-O-DMTr-3'-NH₂-2'-O-Me-dU

≥98% · CAS: 182934-58-3

BX-PN-0053
5'-O-DMTr-5-Me-dC(Bz)

≥98% · CAS: 104579-03-5

BX-PN-0054
5'-O-DMTr-5-O-Me-rU

≥98% · CAS: 2095417-73-3

BX-PN-0055
5'-O-DMTr-N1-Me-pseudoU

≥95% · CAS: 875302-39-9

BX-PN-0056
6'-O-DMTr-2',3'-dideoxy-Homo-C

≥98% · CAS: N/A

BX-PN-0059
5'-O-DMTr-2'-F-dU

Specification on request · CAS: 146954-74-7

BX-PN-0061
5'-O-DMTr-2'-F-dC(Ac)

Specification on request · CAS: 159414-98-9

BX-PN-0062
5'-O-DMTr-2'-F-dG(iBu)

Specification on request · CAS: 144089-96-3

BX-PN-0063
5'-O-DMTr-2'-F-dA(Bz)

Specification on request · CAS: 136834-21-4

BX-PN-0064
5'-O-DMTr-2'-O-Me-rA(Bz)

Specification on request · CAS: 110764-72-2

BX-PN-0065
5'-O-DMTr-2'-O-Me-rC(Ac)

Specification on request · CAS: 199593-08-3

BX-PN-0066
3'-O-DMTr-2'-O-Me-rA(Bz)

Specification on request · CAS: N/A

BX-PN-0075
3',5'-O-DMTr-2'-O-Me-rA(Bz)

Specification on request · CAS: N/A

BX-PN-0076
5'-O-DMTr-2'-O-Me-rA

Specification on request · CAS: 103285-23-0

BX-PN-0077
5'-O-DMTr-3'-O-Me-rA(Bz)

Specification on request · CAS: 127212-38-8

BX-PN-0078
5'-O-DMTr-2'-O-Me-rU

Specification on request · CAS: 103285-22-9

BX-PN-0095
5'-O-DMTr-2'-O-Me-rG(iBu)

Specification on request · CAS: 114745-26-5

BX-PN-0108

Frequently asked questions

What are typical uses for DMTr-protected Nucleosides?

DMTr-protected Nucleosides products serve as starting materials, protected intermediates and analytical comparators in nucleoside, nucleotide and oligonucleotide chemistry.

What should be confirmed before ordering DMTr-protected Nucleosides?

Confirm anomeric and sugar stereochemistry, base identity, substitution position, protecting-group pattern and required downstream transformation.

Are custom quantities or related analogs available?

BX Lab reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.

Need help selecting a product?

Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.

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