DMTr-protected Nucleosides
5'-O-DMTr-3'-O-Me-rA(Bz)
Quick view. N6-Benzoyladenosine bearing a 5'-O-DMTr group and a 3'-O-methyl group, with a free 2'-hydroxyl group. CAS 127212-38-8. Catalog target purity: ≥98%. Availability: Inquiry only; contact BX Lab to confirm current availability.
Product profile
5'-O-DMTr-3'-O-Me-rA(Bz) is classified as dmtr-protected nucleosides.
5'-O-DMTr-3'-O-Me-rA(Bz) can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For 5'-O-DMTr-3'-O-Me-rA(Bz), the 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
Names and search terms
Confirmed or normalized name variants
- N6-Benzoyl-5'-O-DMTr-3'-O-methyladenosine
- 5'-O-DMT-3'-O-Me-rA(Bz)
Useful catalog search terms
- CAS 127212-38-8
- NS067-1
Physicochemical data
| Nucleoside | N6-Benzoyladenosine |
|---|---|
| Hydroxyl protection | 5'-O-DMTr |
| Sugar modification | 3'-O-methyl |
| Hydroxyl state | 2' hydroxyl group unprotected |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 5'-O-DMTr-3'-O-Me-rA(Bz) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-O-DMTr-3'-O-Me-rA(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0078 and CAS 127212-38-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.