Cap Analogs
m7G(5')vppp(5')(2'-OMeA)pG triammonium
Quick view. A vinyl-linked CAP5011 cap analog associated with CAS 3038327-80-6 and presented in triammonium form for mRNA-synthesis research. CAS 3038327-80-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
m7G(5')vppp(5')(2'-OMeA)pG triammonium is classified as cap analogs (Formula C33H52N18O23P4 (triammonium); molecular weight 1192.77 (triammonium)).
m7G(5')vppp(5')(2'-OMeA)pG triammonium — Modified trinucleotide cap analog for mRNA-synthesis research.
For m7G(5')vppp(5')(2'-OMeA)pG triammonium, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP 5 m7G(5')vppp(5')(2'OMeA)pG Ammonium Salt
- CAP 5
- CAP5011
Useful catalog search terms
- CAS 3038327-80-6
Physicochemical data
| Inner-salt formula | C33H43N15O23P4 |
|---|---|
| Inner-salt molecular weight | 1141.68 |
| Counterion form | Triammonium |
| CAS scope | CAP5011 core identity; counterion composition not fixed by CAS |
| Nucleotide shorthand | m7G(5')vppp(5')(2'-OMeA)pG |
| Cap linkage | Vinyl-linked m7G triphosphate |
| First transcribed nucleotide | 2'-O-methyladenosine |
| Covalent InChIKey | FZDGGNDFFHPRBY-SWKUTIIRSA-O |
| Covalent InChI | InChI=1S/C33H43N15O23P4/c1-45-10-48(26-16(45)28(54)44-33(36)42-26)30-19(51)17(49)11(66-30)3-4-72(55,56)70-75(61,62)71-74(59,60)65-6-13-21(22(63-2)31(68-13)46-8-39-14-23(34)37-7-38-24(14)46)69-73(57,58)64-5-12-18(50)20(52)29(67-12)47-9-40-15-25(47)41-32(35)43-27(15)53/h3-4,7-13,17-22,29-31,49-52H,5-6H2,1-2H3,(H11-,34,35,36,37,38,41,42,43,44,53,54,55,56,57,58,59,60,61,62)/p+1/b4-3+/t11-,12-,13-,17-,18-,19-,20-,21-,22-,29-,30-,31-/m1/s1 |
| Covalent SMILES | CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)nc(N)[nH]c43)[C@H](O)[C@@H]2O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)/C=C/[C@H]2O[C@@H](n3c[n+](C)c4c(=O)nc(N)[nH]c43)[C@H](O)[C@@H]2O)O[C@H]1n1cnc2c(N)ncnc21 |
| Canonical covalent SMILES | CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)nc(N)[nH]c43)[C@H](O)[C@@H]2O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)/C=C/[C@H]2O[C@@H](n3c[n+](C)c4c(=O)nc(N)[nH]c43)[C@H](O)[C@@H]2O)O[C@H]1n1cnc2c(N)ncnc21 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe m7G(5')vppp(5')(2'-OMeA)pG triammonium or its named chemical feature. Broader product-family guidance is maintained on the category page.
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BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
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BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
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BX-CA-0007CAP 9 m7G(2'F)(5')ppp(5')(2'OMeA)pG Ammonium Salt
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Frequently asked questions
Can the package size for m7G(5')vppp(5')(2'-OMeA)pG triammonium be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0004 and CAS 3038327-80-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Cap Analogs product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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