Cap Analogs
A(5')ppp(5')(2'-OMeA)pG tetraammonium
Quick view. A no-CAS trinucleotide cap analog in tetraammonium form for co-transcriptional mRNA capping research. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
A(5')ppp(5')(2'-OMeA)pG tetraammonium is classified as cap analogs (Formula C31H41N15O23P4 (free acid); molecular weight 1115.65 (free acid)).
A(5')ppp(5')(2'-OMeA)pG tetraammonium — Trinucleotide cap analog for co-transcriptional mRNA capping in in-vitro-transcription research.
For A(5')ppp(5')(2'-OMeA)pG tetraammonium, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt
- CAP A(5')ppp(5')(2'-OMeA)pG
Physicochemical data
| Counterion form | Tetraammonium |
|---|---|
| Nucleotide shorthand | A(5')ppp(5')(2'-OMeA)pG |
| Nucleotide order | Adenosine - 2'-O-methyladenosine - guanosine |
| Phosphate architecture | 5'-5' triphosphate bridge and one internucleotide phosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe A(5')ppp(5')(2'-OMeA)pG tetraammonium or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
ARCA (m2(7,3'-O)GpppG)
Cap Analogs · CAS: 400806-46-4
BX-CA-0003m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium
Cap Analogs · CAS: N/A
BX-CA-0004m7G(5')vppp(5')(2'-OMeA)pG triammonium
Cap Analogs · CAS: 3038327-80-6
BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0007CAP 9 m7G(2'F)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for A(5')ppp(5')(2'-OMeA)pG tetraammonium be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0002, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Cap Analogs product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.