Other Phosphoramidites
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Quick view. A symmetric bis(phosphoramidite) containing two N2-isobutyryl-5'-O-DMTr-2'-O-MOE guanosine units connected through an oxybis(ethylene) linker. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) is classified as oxybis(ethylene)-linked guanosine bis(phosphoramidite) (Formula C92H120N12O21P2; molecular weight 1791.98).
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) — Bis(phosphoramidite) building block for research-use oligonucleotide synthesis.
For di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite), mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- BOC Sciences BRP-00609
Useful catalog search terms
- BRP-00609
Physicochemical data
| Nucleobase protection | N2-isobutyryl |
|---|---|
| 5' protection | DMTr |
| 2'-Substituent | 2-methoxyethyl |
| Phosphoramidite centers | Two diisopropylphosphoramidite groups |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-OP-00025'-O-DMTr-2'-O-MOE-5-Me-rC(Bz) Bis(phosphoramidite)
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BX-OP-00035'-O-DMTr-2'-O-MOE-rG(iBu) Bis(phosphoramidite)
Other Phosphoramidites · CAS: N/A
BX-OP-00045'-O-DMTr-2'-O-MOE-rT Bis(phosphoramidite)
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BX-OP-00065'-DMT Amino-Modifier C6 Phosphoramidite
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BX-OP-0007Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite
Other Phosphoramidites · CAS: N/A
Frequently asked questions
Can the package size for di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-OP-0062, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Other Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.