2'-Fluoro Phosphoramidites
DMTr-2'-F-dT-3'-CE-Phosphoramidite
Quick view. A protected 2'-fluoro thymidine CE phosphoramidite building block for research-use oligonucleotide synthesis. CAS 182700-06-7. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-F-dT-3'-CE-Phosphoramidite is classified as protected 2'-fluoro thymidine ce phosphoramidite (Formula C40H48FN4O8P; molecular weight 762.80).
DMTr-2'-F-dT-3'-CE-Phosphoramidite — This protected 2'-fluoro thymidine CE phosphoramidite is cataloged as a building block for research-use oligonucleotide synthesis.
For DMTr-2'-F-dT-3'-CE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-F-dT-3'-CE-Phosphoramidite
- 2'-Fluoro-5-Me-U-3'-CE-Phosphoramidite
- 5-Methyl-2'-Fluoro-U CE Phosphoramidite
Useful catalog search terms
- CAS 182700-06-7
- PubChem CID 15516161
- C40H48FN4O8P
Physicochemical data
| PubChem CID | 15516161 |
|---|---|
| InChIKey | XUCJAZSCNJHDKP-ANEPUODISA-N |
| 5' protection | 4,4'-Dimethoxytrityl (DMTr) |
| Sugar modification | 2'-fluoro |
| Nucleobase | 5-methyluracil (thymine) |
| 3'-function | 2-cyanoethyl N,N-diisopropyl phosphoramidite |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe DMTr-2'-F-dT-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2FP-0003DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0004DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0005DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0006DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 3081868-42-7
Frequently asked questions
Can the package size for DMTr-2'-F-dT-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0009 and CAS 182700-06-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.